Do I have to have/wear a synthetic wig while under going chemotherapy? The short answer is NO. I had someone reach out to me through a direct message after I made an online post in a hair community page. She was adamant that cancer patients should only have synthetic wigs. She went on to say that the cancer society does not endorse human hair wigs nor does the Look Good Feel Better foundation. I disagree with her. Cancer treatments can be aggressive and very taxing on the bo